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Coordinate post-transcriptional repression of Dpp-dependent transcription factors attenuates signal range during development

Precise control of the range of signalling molecule action is crucial for correct cell fate patterning during development. For example, Drosophila ovarian germline stem cells (GSCs) are maintained by exquisitely short-range BMP signalling from the niche. In the absence of BMP signalling, one GSC dau...

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Detalles Bibliográficos
Autores principales: Newton, Fay G., Harris, Robin E., Sutcliffe, Catherine, Ashe, Hilary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631754/
https://www.ncbi.nlm.nih.gov/pubmed/26293305
http://dx.doi.org/10.1242/dev.123273