T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice

Chronic lymphocytic leukaemia (CLL) cells require microenvironmental support for their proliferation. This can be recapitulated in highly immunocompromised hosts in the presence of T cells and other supporting cells. Current primary CLL xenograft models suffer from limited duration of tumour cell en...

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Detalles Bibliográficos
Autores principales: Oldreive, Ceri E., Skowronska, Anna, Davies, Nicholas J., Parry, Helen, Agathanggelou, Angelo, Krysov, Sergey, Packham, Graham, Rudzki, Zbigniew, Cronin, Laura, Vrzalikova, Katerina, Murray, Paul, Odintsova, Elena, Pratt, Guy, Taylor, A. Malcolm R., Moss, Paul, Stankovic, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631786/
https://www.ncbi.nlm.nih.gov/pubmed/26398941
http://dx.doi.org/10.1242/dmm.021147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631786/
https://www.ncbi.nlm.nih.gov/pubmed/26398941
http://dx.doi.org/10.1242/dmm.021147

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