Loss of the Coffin-Lowry syndrome-associated gene RSK2 alters ERK activity, synaptic function and axonal transport in Drosophila motoneurons

Plastic changes in synaptic properties are considered as fundamental for adaptive behaviors. Extracellular-signal-regulated kinase (ERK)-mediated signaling has been implicated in regulation of synaptic plasticity. Ribosomal S6 kinase 2 (RSK2) acts as a regulator and downstream effector of ERK. In th...

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Detalles Bibliográficos
Autores principales: Beck, Katherina, Ehmann, Nadine, Andlauer, Till F. M., Ljaschenko, Dmitrij, Strecker, Katrin, Fischer, Matthias, Kittel, Robert J., Raabe, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631788/
https://www.ncbi.nlm.nih.gov/pubmed/26398944
http://dx.doi.org/10.1242/dmm.021246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631788/
https://www.ncbi.nlm.nih.gov/pubmed/26398944
http://dx.doi.org/10.1242/dmm.021246

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