Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

Staphylococcus aureus necrotizing pneumonia is recognized as a toxin-mediated disease, yet the tissue-destructive events remain elusive, partly as a result of lack of mechanistic studies in human lung tissue. In this study, a three-dimensional (3D) tissue model composed of human lung epithelial cell...

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Detalles Bibliográficos
Autores principales: Mairpady Shambat, Srikanth, Chen, Puran, Nguyen Hoang, Anh Thu, Bergsten, Helena, Vandenesch, Francois, Siemens, Nikolai, Lina, Gerard, Monk, Ian R., Foster, Timothy J., Arakere, Gayathri, Svensson, Mattias, Norrby-Teglund, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631791/
https://www.ncbi.nlm.nih.gov/pubmed/26398950
http://dx.doi.org/10.1242/dmm.021923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631791/
https://www.ncbi.nlm.nih.gov/pubmed/26398950
http://dx.doi.org/10.1242/dmm.021923

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