Deposition pattern and subcellular distribution of disease-associated prion protein in cerebellar organotypic slice cultures infected with scrapie

Organotypic cerebellar slices represent a suitable model for characterizing and manipulating prion replication in complex cell environments. Organotypic slices recapitulate prion pathology and are amenable to drug testing in the absence of a blood-brain-barrier. So far, the cellular and subcellular...

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Detalles Bibliográficos
Autores principales: Wolf, Hanna, Hossinger, André, Fehlinger, Andrea, Büttner, Sven, Sim, Valerie, McKenzie, Debbie, Vorberg, Ina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631830/
https://www.ncbi.nlm.nih.gov/pubmed/26581229
http://dx.doi.org/10.3389/fnins.2015.00410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631830/
https://www.ncbi.nlm.nih.gov/pubmed/26581229
http://dx.doi.org/10.3389/fnins.2015.00410

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