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Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy

Natural Killer T (NKT) cells are unique lymphocytes characterized by their expression of a single invariant antigen receptor encoded by Vα14Jα18 in mice and Vα24Jα18 in humans, which recognizes glycolipid antigens in association with the monomorphic CD1d molecule. NKT cells mediate adjuvant activity...

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Detalles Bibliográficos
Autores principales: TANIGUCHI, Masaru, HARADA, Michishige, DASHTSOODOL, Nyambayar, KOJO, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631895/
https://www.ncbi.nlm.nih.gov/pubmed/26194854
http://dx.doi.org/10.2183/pjab.91.292