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A new conceptual framework for investigating complex genetic disease
Some common diseases are known to have an inherited component, however, their population- and familial-incidence patterns do not conform to any known monogenic Mendelian pattern of inheritance and instead they are currently much better explained if an underlying polygenic architecture is posited. St...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631989/ https://www.ncbi.nlm.nih.gov/pubmed/26583033 http://dx.doi.org/10.3389/fgene.2015.00327 |