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A new conceptual framework for investigating complex genetic disease

Some common diseases are known to have an inherited component, however, their population- and familial-incidence patterns do not conform to any known monogenic Mendelian pattern of inheritance and instead they are currently much better explained if an underlying polygenic architecture is posited. St...

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Detalles Bibliográficos
Autor principal: Hussain, Shobbir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631989/
https://www.ncbi.nlm.nih.gov/pubmed/26583033
http://dx.doi.org/10.3389/fgene.2015.00327