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A new conceptual framework for investigating complex genetic disease
Some common diseases are known to have an inherited component, however, their population- and familial-incidence patterns do not conform to any known monogenic Mendelian pattern of inheritance and instead they are currently much better explained if an underlying polygenic architecture is posited. St...
Autor principal: | Hussain, Shobbir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631989/ https://www.ncbi.nlm.nih.gov/pubmed/26583033 http://dx.doi.org/10.3389/fgene.2015.00327 |
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