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Single-Dose Anti-CD138 Radioimmunotherapy: Bismuth-213 is More Efficient than Lutetium-177 for Treatment of Multiple Myeloma in a Preclinical Model

OBJECTIVES: Radioimmunotherapy (RIT) has emerged as a potential treatment option for multiple myeloma (MM). In humans, a dosimetry study recently showed the relevance of RIT using an antibody targeting the CD138 antigen. The therapeutic efficacy of RIT using an anti-CD138 antibody coupled to (213)Bi...

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Detalles Bibliográficos
Autores principales: Fichou, Nolwenn, Gouard, Sébastien, Maurel, Catherine, Barbet, Jacques, Ferrer, Ludovic, Morgenstern, Alfred, Bruchertseifer, Frank, Faivre-Chauvet, Alain, Bigot-Corbel, Edith, Davodeau, François, Gaschet, Joëlle, Chérel, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631990/
https://www.ncbi.nlm.nih.gov/pubmed/26582128
http://dx.doi.org/10.3389/fmed.2015.00076