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CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy

RNA binding protein is identified as an important mediator of aberrant alternative splicing in muscle atrophy. The altered splicing of calcium channels, such as ryanodine receptors (RyRs), plays an important role in impaired excitation-contraction (E-C) coupling in muscle atrophy; however, the regul...

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Detalles Bibliográficos
Autores principales: Tang, Yinglong, Wang, Huiwen, Wei, Bin, Guo, Yuting, Gu, Lei, Yang, Zhiguang, Zhang, Qing, Wu, Yanyun, Yuan, Qi, Zhao, Gang, Ji, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632035/
https://www.ncbi.nlm.nih.gov/pubmed/26531141
http://dx.doi.org/10.1038/srep16083