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CUG-BP1 regulates RyR1 ASI alternative splicing in skeletal muscle atrophy
RNA binding protein is identified as an important mediator of aberrant alternative splicing in muscle atrophy. The altered splicing of calcium channels, such as ryanodine receptors (RyRs), plays an important role in impaired excitation-contraction (E-C) coupling in muscle atrophy; however, the regul...
Autores principales: | Tang, Yinglong, Wang, Huiwen, Wei, Bin, Guo, Yuting, Gu, Lei, Yang, Zhiguang, Zhang, Qing, Wu, Yanyun, Yuan, Qi, Zhao, Gang, Ji, Guangju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632035/ https://www.ncbi.nlm.nih.gov/pubmed/26531141 http://dx.doi.org/10.1038/srep16083 |
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