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Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes

Bladder cancer, the fourth most common noncutaneous malignancy in the United States, is characterized by high recurrence rate, with a subset of these cancers progressing to a deadly muscle invasive form of disease. Exosomes are small secreted vesicles that contain proteins, mRNA and miRNA, thus pote...

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Detalles Bibliográficos
Autores principales: Franzen, C A, Blackwell, R H, Todorovic, V, Greco, K A, Foreman, K E, Flanigan, R C, Kuo, P C, Gupta, G N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632072/
https://www.ncbi.nlm.nih.gov/pubmed/26280654
http://dx.doi.org/10.1038/oncsis.2015.21