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No effect on pharmacokinetics of tamoxifen and 4-hydroxytamoxifen by multiple doses of red clover capsule in rats

Tamoxifen is used in clinical practice for breast cancer patients and to prevent osteoporosis. Red clover (Trifolium pratense) preparations are consumed worldwide as dietary supplements for relieving postmenopausal symptoms. In the present study we investigated the possible herb-drug interaction bet...

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Detalles Bibliográficos
Autores principales: Raju, Kanumuri Siva Rama, Taneja, Isha, Valicherla, Guru Raghavendra, Challagundla, Murali Krishna, Rashid, Mamunur, Syed, Anees Ahmed, Gayen, Jiaur Rahman, Singh, Sheelendra Pratap, Wahajuddin, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632083/
https://www.ncbi.nlm.nih.gov/pubmed/26530625
http://dx.doi.org/10.1038/srep16126