Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer’s disease

The human β-amyloid (Aβ) cleaving enzyme (BACE-1) is a target for Alzheimer’s disease (AD) treatments. This study was conducted to determine if acacetin extracted from the whole Agastache rugosa plant had anti-BACE-1 and behavioral activities in Drosophila melanogaster AD models and to determine aca...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Perumalsamy, Haribalan, Kwon, Hyung Wook, Na, Young-Eun, Ahn, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632086/
https://www.ncbi.nlm.nih.gov/pubmed/26530776
http://dx.doi.org/10.1038/srep16127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632086/
https://www.ncbi.nlm.nih.gov/pubmed/26530776
http://dx.doi.org/10.1038/srep16127

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