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Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis

Although RNA interference (RNAi) knockdown screening of cancer cell cultures is an effective approach to predict drug targets or therapeutic/prognostic biomarkers, interactions among identified targets often remain obscure. Here, we introduce the nodes-and-connections RNAi knockdown screening that g...

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Detalles Bibliográficos
Autores principales: Miyoshi, N, Wittner, B S, Shioda, K, Hitora, T, Ito, T, Ramaswamy, S, Isselbacher, K J, Sgroi, D C, Shioda, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632093/
https://www.ncbi.nlm.nih.gov/pubmed/26479444
http://dx.doi.org/10.1038/oncsis.2015.32