Comparison of Macitentan and Bosentan on Right Ventricular Remodeling in a Rat Model of Non-vasoreactive Pulmonary Hypertension

We compared the efficacy of macitentan, a novel dual endothelin A/endothelin B receptor antagonist, with that of another dual endothelin receptor antagonist, bosentan, in a rat model of non-vasoreactive pulmonary hypertension (PH) with particular emphasis on right ventricular (RV) remodeling. METHOD...

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Detalles Bibliográficos
Autores principales: Iglarz, Marc, Landskroner, Kyle, Bauer, Yasmina, Vercauteren, Magali, Rey, Markus, Renault, Berengère, Studer, Rolf, Vezzali, Enrico, Freti, Diego, Hadana, Hakim, Schläpfer, Manuela, Cattaneo, Christophe, Bortolamiol, Céline, Weber, Edgar, Whitby, Brian R., Delahaye, Stéphane, Wanner, Daniel, Steiner, Pauline, Nayler, Oliver, Hess, Patrick, Clozel, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632117/
https://www.ncbi.nlm.nih.gov/pubmed/26230396
http://dx.doi.org/10.1097/FJC.0000000000000296