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Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase

BACKGROUND: The selective estrogen receptor modulator tamoxifen, in combination with the Cre-ER(T2) fusion protein, has been one of the mainstream methods to induce genetic recombination and has found widespread application in lineage tracing studies. METHODS & RESULTS: Here, we report that tamo...

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Detalles Bibliográficos
Autores principales: Ye, Risheng, Wang, Qiong A., Tao, Caroline, Vishvanath, Lavanya, Shao, Mengle, McDonald, Jeffery G., Gupta, Rana K., Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632120/
https://www.ncbi.nlm.nih.gov/pubmed/26629402
http://dx.doi.org/10.1016/j.molmet.2015.08.004