Cargando…
Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase
BACKGROUND: The selective estrogen receptor modulator tamoxifen, in combination with the Cre-ER(T2) fusion protein, has been one of the mainstream methods to induce genetic recombination and has found widespread application in lineage tracing studies. METHODS & RESULTS: Here, we report that tamo...
Autores principales: | Ye, Risheng, Wang, Qiong A., Tao, Caroline, Vishvanath, Lavanya, Shao, Mengle, McDonald, Jeffery G., Gupta, Rana K., Scherer, Philipp E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632120/ https://www.ncbi.nlm.nih.gov/pubmed/26629402 http://dx.doi.org/10.1016/j.molmet.2015.08.004 |
Ejemplares similares
-
Cold-responsive adipocyte progenitors couple adrenergic signaling to immune cell activation to promote beige adipocyte accrual
por: Shan, Bo, et al.
Publicado: (2021) -
Dual Cre and Dre recombinases mediate synchronized lineage tracing and cell subset ablation in vivo
por: Wang, Haixiao, et al.
Publicado: (2022) -
Transgenic Mice for a Tamoxifen-Induced, Conditional Expression of the Cre Recombinase in Osteoclasts
por: Sanchez-Fernandez, Maria Arantzazu, et al.
Publicado: (2012) -
Characterization of Cre Recombinase Activity for In Vivo Targeting of Adipocyte Precursor Cells
por: Krueger, Katherine C., et al.
Publicado: (2014) -
Tamoxifen Activation of Cre-Recombinase Has No Persisting Effects on Adult Neurogenesis or Learning and Anxiety
por: Rotheneichner, Peter, et al.
Publicado: (2017)