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High specific selectivity and Membrane-Active Mechanism of the synthetic centrosymmetric α-helical peptides with Gly-Gly pairs

We used a template-assisted approach to develop synthetic antimicrobial peptides, which differ from naturally occurring antimicrobial peptides that can compromise host natural defenses. Previous researches have demonstrated that symmetrical distribution patterns of amino acids contribute to the anti...

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Detalles Bibliográficos
Autores principales: Wang, Jiajun, Chou, Shuli, Xu, Lin, Zhu, Xin, Dong, Na, Shan, Anshan, Chen, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632126/
https://www.ncbi.nlm.nih.gov/pubmed/26530005
http://dx.doi.org/10.1038/srep15963