SEC14L2 enables pan-genotype HCV replication in cell culture

Since its discovery in 1989, efforts to grow clinical isolates of the hepatitis C virus (HCV) in cell culture have met with limited success. Only the JFH-1 isolate has the capacity to replicate efficiently in cultured hepatoma cells without cell culture-adaptive mutations(1-3). We hypothesized that...

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Detalles Bibliográficos
Autores principales: Saeed, Mohsan, Andreo, Ursula, Chung, Hyo-Young, Espiritu, Christine, Branch, Andrea D., Silva, Jose M., Rice, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632207/
https://www.ncbi.nlm.nih.gov/pubmed/26266980
http://dx.doi.org/10.1038/nature14899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632207/
https://www.ncbi.nlm.nih.gov/pubmed/26266980
http://dx.doi.org/10.1038/nature14899

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