Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome

Alterations in the scaffold protein WRAP53β have previously been linked to carcinogenesis and, in particular, associated with an increased risk for epithelial ovarian cancer. Here, we investigated the pathogenic impact and prognostic significance of WRAP53β in connection with epithelial ovarian canc...

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Detalles Bibliográficos
Autores principales: Hedström, E, Pederiva, C, Farnebo, J, Nodin, B, Jirström, K, Brennan, D J, Farnebo, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632285/
https://www.ncbi.nlm.nih.gov/pubmed/26426684
http://dx.doi.org/10.1038/cddis.2015.250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632285/
https://www.ncbi.nlm.nih.gov/pubmed/26426684
http://dx.doi.org/10.1038/cddis.2015.250

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