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miR-300 mediates Bmi1 function and regulates differentiation in primitive cardiac progenitors

B lymphoma Mo-MLV insertion region 1 (Bmi1) is a polycomb-family transcriptional factor critical for self-renewal in many adult stem cells and human neoplasia. We sought to identify microRNAs regulated by Bmi1 that could play a role in multipotent cardiac progenitor cell (CPC) decisions. We found th...

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Detalles Bibliográficos
Autores principales: Cruz, F M, Tomé, M, Bernal, J A, Bernad, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632286/
https://www.ncbi.nlm.nih.gov/pubmed/26512961
http://dx.doi.org/10.1038/cddis.2015.255