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The RCAN1 inhibits NF-κB and suppresses lymphoma growth in mice

Nuclear factor-κB (NF-κB) has a vital role in cell survival. Inhibition of NF-κB has been proven to be an efficient therapeutic pathway for various cancers. Activation of NF-κB is mainly through serine residues' phosphorylation of inhibitor of κBα (IκBα) by IKK complex. Phosphorylation at tyros...

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Detalles Bibliográficos
Autores principales: Liu, C, Zheng, L, Wang, H, Ran, X, Liu, H, Sun, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632290/
https://www.ncbi.nlm.nih.gov/pubmed/26492364
http://dx.doi.org/10.1038/cddis.2015.260