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EphB3 receptors function as dependence receptors to mediate oligodendrocyte cell death following contusive spinal cord injury

We demonstrate that EphB3 receptors mediate oligodendrocyte (OL) cell death in the injured spinal cord through dependence receptor mechanism. OLs in the adult spinal cord express EphB3 as well as other members of the Eph receptor family. Spinal cord injury (SCI) is associated with tissue damage, cel...

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Detalles Bibliográficos
Autores principales: Tsenkina, Y, Ricard, J, Runko, E, Quiala- Acosta, M M, Mier, J, Liebl, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632292/
https://www.ncbi.nlm.nih.gov/pubmed/26469970
http://dx.doi.org/10.1038/cddis.2015.262