Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner

Chemoresistance in cancer has previously been attributed to gene mutations or deficiencies. Bax or p53 deficiency can lead to resistance to cancer drugs. We aimed to find an agent to overcome chemoresistance induced by Bax or p53 deficiency. Here, we used immunoblot, flow-cytometry analysis, gene in...

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Detalles Bibliográficos
Autores principales: Guo, W, Zhang, Y, Ling, Z, Liu, X, Zhao, X, Yuan, Z, Nie, C, Wei, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632302/
https://www.ncbi.nlm.nih.gov/pubmed/26469967
http://dx.doi.org/10.1038/cddis.2015.276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632302/
https://www.ncbi.nlm.nih.gov/pubmed/26469967
http://dx.doi.org/10.1038/cddis.2015.276

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