NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1

Degradation of malfunctional mitochondria by mitophagy is a pivotal component of mitochondrial quality control to maintain cellular homeostasis. Mitochondrial clearance through the PINK1/PARK2 pathway is mediated by autophagic adaptor proteins. Previous studies revealed a significant involvement, bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, J, Fung, G, Deng, H, Zhang, J, Fiesel, F C, Springer, W, Li, X, Luo, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632303/
https://www.ncbi.nlm.nih.gov/pubmed/26512954
http://dx.doi.org/10.1038/cddis.2015.278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632303/
https://www.ncbi.nlm.nih.gov/pubmed/26512954
http://dx.doi.org/10.1038/cddis.2015.278

Ejemplares similares