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A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy

Molecular mechanisms protecting cardiomyocytes from stress-induced death, including tension stress, are essential for cardiac physiology and defects in these protective mechanisms can result in pathological alterations. Bcl2-associated athanogene 3 (BAG3) is expressed in cardiomyocytes and is a comp...

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Detalles Bibliográficos
Autores principales: d'Avenia, M, Citro, R, De Marco, M, Veronese, A, Rosati, A, Visone, R, Leptidis, S, Philippen, L, Vitale, G, Cavallo, A, Silverio, A, Prota, C, Gravina, P, De Cola, A, Carletti, E, Coppola, G, Gallo, S, Provenza, G, Bossone, E, Piscione, F, Hahne, M, De Windt, L J, Turco, M C, De Laurenzi, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632305/
https://www.ncbi.nlm.nih.gov/pubmed/26512958
http://dx.doi.org/10.1038/cddis.2015.280