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A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy
Molecular mechanisms protecting cardiomyocytes from stress-induced death, including tension stress, are essential for cardiac physiology and defects in these protective mechanisms can result in pathological alterations. Bcl2-associated athanogene 3 (BAG3) is expressed in cardiomyocytes and is a comp...
Autores principales: | d'Avenia, M, Citro, R, De Marco, M, Veronese, A, Rosati, A, Visone, R, Leptidis, S, Philippen, L, Vitale, G, Cavallo, A, Silverio, A, Prota, C, Gravina, P, De Cola, A, Carletti, E, Coppola, G, Gallo, S, Provenza, G, Bossone, E, Piscione, F, Hahne, M, De Windt, L J, Turco, M C, De Laurenzi, V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632305/ https://www.ncbi.nlm.nih.gov/pubmed/26512958 http://dx.doi.org/10.1038/cddis.2015.280 |
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