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Proteasomal inhibition sensitizes cervical cancer cells to mitomycin C-induced bystander effect: the role of tumor microenvironment

Inaccessibility of drugs to poorly vascularized strata of tumor is one of the limiting factors in cancer therapy. With the advent of bystander effect (BE), it is possible to perpetuate the cellular damage from drug-exposed cells to the unexposed ones. However, the role of infiltrating tumor-associat...

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Detalles Bibliográficos
Autores principales: Singh, S V, Ajay, A K, Mohammad, N, Malvi, P, Chaube, B, Meena, A S, Bhat, M K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632313/
https://www.ncbi.nlm.nih.gov/pubmed/26492368
http://dx.doi.org/10.1038/cddis.2015.292