Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells

Platinum-based drugs remain as the cornerstone of cancer chemotherapy; however, development of multidrug resistance presents a therapeutic challenge. This study aims at understanding the molecular mechanisms underlying resistance to cisplatin and unraveling surrogate signaling networks that could re...

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Detalles Bibliográficos
Autores principales: Seah, S, Low, I C C, Hirpara, J L, Sachaphibulkij, K, Kroemer, G, Brenner, C, Pervaiz, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632318/
https://www.ncbi.nlm.nih.gov/pubmed/26492363
http://dx.doi.org/10.1038/cddis.2015.299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632318/
https://www.ncbi.nlm.nih.gov/pubmed/26492363
http://dx.doi.org/10.1038/cddis.2015.299

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