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Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells
Platinum-based drugs remain as the cornerstone of cancer chemotherapy; however, development of multidrug resistance presents a therapeutic challenge. This study aims at understanding the molecular mechanisms underlying resistance to cisplatin and unraveling surrogate signaling networks that could re...
Autores principales: | Seah, S, Low, I C C, Hirpara, J L, Sachaphibulkij, K, Kroemer, G, Brenner, C, Pervaiz, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632318/ https://www.ncbi.nlm.nih.gov/pubmed/26492363 http://dx.doi.org/10.1038/cddis.2015.299 |
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