Impact of the combined loss of BOK, BAX and BAK on the hematopoietic system is slightly more severe than compound loss of BAX and BAK

It is well established that BAX and BAK play crucial, overlapping roles in the intrinsic pathway of apoptosis. Gene targeted mice lacking both BAX and BAK have previously been generated, but the majority of these animals died perinatally. BOK is a poorly studied relative of BAX and BAK that shares e...

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Detalles Bibliográficos
Autores principales: Ke, F, Grabow, S, Kelly, G L, Lin, A, O'Reilly, L A, Strasser, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632322/
https://www.ncbi.nlm.nih.gov/pubmed/26492371
http://dx.doi.org/10.1038/cddis.2015.304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632322/
https://www.ncbi.nlm.nih.gov/pubmed/26492371
http://dx.doi.org/10.1038/cddis.2015.304

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