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Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicity

Kinase D-interacting substrate of 220 kDa (Kidins220), also known as ankyrin repeat-rich membrane spanning (ARMS), has a central role in the coordination of receptor crosstalk and the integration of signaling pathways essential for neuronal differentiation, survival and function. This protein is a s...

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Detalles Bibliográficos
Autores principales: Gamir-Morralla, A, López-Menéndez, C, Ayuso-Dolado, S, Tejeda, G S, Montaner, J, Rosell, A, Iglesias, T, Díaz-Guerra, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632323/
https://www.ncbi.nlm.nih.gov/pubmed/26492372
http://dx.doi.org/10.1038/cddis.2015.307