A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties

INTRODUCTION: Activation of cyclooxygenase (COX)/prostaglandin and nuclear factor κB (NFκB) pathways can promote breast tumor initiation, growth, and progression to drug resistance and metastasis. Thus, anti-inflammatory drugs have been widely explored as chemopreventive and antineoplastic agents. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Kastrati, Irida, Litosh, Vladislav A., Zhao, Shuangping, Alvarez, Manuel, Thatcher, Gregory R. J., Frasor, Jonna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632459/
https://www.ncbi.nlm.nih.gov/pubmed/26530254
http://dx.doi.org/10.1186/s12885-015-1868-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632459/
https://www.ncbi.nlm.nih.gov/pubmed/26530254
http://dx.doi.org/10.1186/s12885-015-1868-7

Ejemplares similares