A novel method to detect articular chondrocyte death during early stages of osteoarthritis using a non-invasive ApoPep-1 probe

INTRODUCTION: Current methods for early diagnosis of osteoarthritis (OA) are limited. We assessed whether in vivo detection of chondrocyte death by ApoPep-1 (CQRPPR), a peptide that binds to histone H1 of apoptotic and necrotic cells, could be used to detect the initiation of OA. METHODS: Apoptosis-...

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Detalles Bibliográficos
Autores principales: Che, Xiangguo, Chi, Lianhua, Park, Clara Yongjoo, Cho, Gyoung-Ho, Park, Narae, Kim, Seong-Gon, Lee, Byung-Heon, Choi, Je-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632461/
https://www.ncbi.nlm.nih.gov/pubmed/26530111
http://dx.doi.org/10.1186/s13075-015-0832-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632461/
https://www.ncbi.nlm.nih.gov/pubmed/26530111
http://dx.doi.org/10.1186/s13075-015-0832-x

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