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Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines

BACKGROUND: Phospholipases A(2) (PLA(2)s) are abundant components of snake venoms that have been extensively studied due to their pharmacological and pathophysiological effects on living organisms. This study aimed to assess the antitumor potential of BthTX-I, a basic myotoxic PLA(2) isolated from B...

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Detalles Bibliográficos
Autores principales: Prinholato da Silva, Cássio, Costa, Tássia R., Paiva, Raquel M. Alves, Cintra, Adélia C. O., Menaldo, Danilo L., Antunes, Lusânia M. Greggi, Sampaio, Suely V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632473/
https://www.ncbi.nlm.nih.gov/pubmed/26539212
http://dx.doi.org/10.1186/s40409-015-0044-5