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Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA

DNA methylation occurs on CpG sites and is important to form pericentric heterochromatin domains. The satellite 2 sequence, containing seven CpG sites, is located in the pericentric region of human chromosome 1 and is highly methylated in normal cells. In contrast, the satellite 2 region is reported...

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Detalles Bibliográficos
Autores principales: Osakabe, Akihisa, Adachi, Fumiya, Arimura, Yasuhiro, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632512/
https://www.ncbi.nlm.nih.gov/pubmed/26446621
http://dx.doi.org/10.1098/rsob.150128