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Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival

BACKGROUND: Kv10.1, a voltage-gated potassium channel only detected in the healthy brain, was found to be aberrantly expressed in extracerebral cancers. Investigations of Kv10.1 in brain metastasis and glioblastoma multiforme (GBM) are lacking. METHODS: We analyzed the expression of Kv10.1 by immuno...

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Detalles Bibliográficos
Autores principales: Martínez, Ramón, Stühmer, Walter, Martin, Sabine, Schell, Julian, Reichmann, Andrea, Rohde, Veit, Pardo, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632660/
https://www.ncbi.nlm.nih.gov/pubmed/26530050
http://dx.doi.org/10.1186/s12885-015-1848-y