The function, regulation and therapeutic implications of the tumor suppressor protein, PML

The tumor suppressor protein, promyelocytic leukemia protein (PML), was originally identified in acute promyelocytic leukemia due to a chromosomal translocation between chromosomes 15 and 17. PML is the core component of subnuclear structures called PML nuclear bodies (PML-NBs), which are disrupted...

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Detalles Bibliográficos
Autores principales: Guan, Dongyin, Kao, Hung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632682/
https://www.ncbi.nlm.nih.gov/pubmed/26539288
http://dx.doi.org/10.1186/s13578-015-0051-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632682/
https://www.ncbi.nlm.nih.gov/pubmed/26539288
http://dx.doi.org/10.1186/s13578-015-0051-9

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