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The function, regulation and therapeutic implications of the tumor suppressor protein, PML
The tumor suppressor protein, promyelocytic leukemia protein (PML), was originally identified in acute promyelocytic leukemia due to a chromosomal translocation between chromosomes 15 and 17. PML is the core component of subnuclear structures called PML nuclear bodies (PML-NBs), which are disrupted...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632682/ https://www.ncbi.nlm.nih.gov/pubmed/26539288 http://dx.doi.org/10.1186/s13578-015-0051-9 |