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Combining Protein and Strain Engineering for the Production of Glyco-Engineered Horseradish Peroxidase C1A in Pichia pastoris

Horseradish peroxidase (HRP), conjugated to antibodies and lectins, is widely used in medical diagnostics. Since recombinant production of the enzyme is difficult, HRP isolated from plant is used for these applications. Production in the yeast Pichia pastoris (P. pastoris), the most promising recomb...

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Detalles Bibliográficos
Autores principales: Capone, Simona, Ćorajević, Lejla, Bonifert, Günther, Murth, Patrick, Maresch, Daniel, Altmann, Friedrich, Herwig, Christoph, Spadiut, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632689/
https://www.ncbi.nlm.nih.gov/pubmed/26404235
http://dx.doi.org/10.3390/ijms161023127