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Combining Protein and Strain Engineering for the Production of Glyco-Engineered Horseradish Peroxidase C1A in Pichia pastoris
Horseradish peroxidase (HRP), conjugated to antibodies and lectins, is widely used in medical diagnostics. Since recombinant production of the enzyme is difficult, HRP isolated from plant is used for these applications. Production in the yeast Pichia pastoris (P. pastoris), the most promising recomb...
Autores principales: | Capone, Simona, Ćorajević, Lejla, Bonifert, Günther, Murth, Patrick, Maresch, Daniel, Altmann, Friedrich, Herwig, Christoph, Spadiut, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632689/ https://www.ncbi.nlm.nih.gov/pubmed/26404235 http://dx.doi.org/10.3390/ijms161023127 |
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