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Secreted Frizzled-Related Protein Promotes Bone Regeneration by Human Bone Marrow-Derived Mesenchymal Stem Cells

Secreted frizzled-related protein (sFRP)-3 is a negative regulator of Wnt signaling in human mesenchymal stem cells (hMSCs). The present study investigated the effects sFRP-3 on osteogenic differentiation by assessing osteogenic gene expression in hMSCs in vitro and by examining bone regeneration in...

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Detalles Bibliográficos
Autores principales: Katagiri, Wataru, Osugi, Masashi, Kawai, Takamasa, Hibi, Hideharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632696/
https://www.ncbi.nlm.nih.gov/pubmed/26404242
http://dx.doi.org/10.3390/ijms161023250