Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step

Often when generating recombinant affinity reagents to a target, one singles out an individual binder, constructs a secondary library of variants, and affinity selects a tighter or more specific binder. To enhance the throughput of this general approach, we have developed a more integrated strategy...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Renhua, Gorman, Kevin T., Vinci, Chris R., Dobrovetsky, Elena, Gräslund, Susanne, Kay, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632715/
https://www.ncbi.nlm.nih.gov/pubmed/26437402
http://dx.doi.org/10.3390/ijms161023587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632715/
https://www.ncbi.nlm.nih.gov/pubmed/26437402
http://dx.doi.org/10.3390/ijms161023587

Ejemplares similares