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Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine

Shikonin is an anthraquinone derivative extracted from the root of lithospermum. Shikonin is traditionally used in the treatment of inflammatory and infectious diseases such as hepatitis. Shikonin also inhibits proliferation and induces apoptosis in various tumors. However, the effect of shikonin on...

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Detalles Bibliográficos
Autores principales: Zhang, Feng-Ying, Hu, Yi, Que, Zhong-You, Wang, Ping, Liu, Yun-Hui, Wang, Zhen-Hua, Xue, Yi-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632727/
https://www.ncbi.nlm.nih.gov/pubmed/26473829
http://dx.doi.org/10.3390/ijms161023823