Cargando…
Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine
Shikonin is an anthraquinone derivative extracted from the root of lithospermum. Shikonin is traditionally used in the treatment of inflammatory and infectious diseases such as hepatitis. Shikonin also inhibits proliferation and induces apoptosis in various tumors. However, the effect of shikonin on...
Autores principales: | Zhang, Feng-Ying, Hu, Yi, Que, Zhong-You, Wang, Ping, Liu, Yun-Hui, Wang, Zhen-Hua, Xue, Yi-Xue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632727/ https://www.ncbi.nlm.nih.gov/pubmed/26473829 http://dx.doi.org/10.3390/ijms161023823 |
Ejemplares similares
-
Shikonin induces apoptosis and inhibits migration of ovarian carcinoma cells by inhibiting the phosphorylation of Src and FAK
por: HAO, ZHENFENG, et al.
Publicado: (2015) -
Topoisomerase I Inhibitors, Shikonin and Topotecan, Inhibit Growth and Induce Apoptosis of Glioma Cells and Glioma Stem Cells
por: Zhang, Feng-Lei, et al.
Publicado: (2013) -
Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT
por: Xu, Yi, et al.
Publicado: (2018) -
Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKKβ Activity and JNK Phosphorylation
por: Li, Ting, et al.
Publicado: (2013) -
An Oxidative Stress Mechanism of Shikonin in Human Glioma Cells
por: Yang, Jen-Tsung, et al.
Publicado: (2014)