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Mutational Spectrum Analysis of Neurodegenerative Diseases and Its Pathogenic Implication

One of the most conspicuous features of neurodegenerative diseases (NDs) is the occurrence of dramatic conformation change of individual proteins. We performed a mutational spectrum analysis of disease-causing missense mutations in seven types of NDs at nucleotide and amino acid levels, and compared...

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Detalles Bibliográficos
Autores principales: Shen, Liang, Ji, Hong-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632750/
https://www.ncbi.nlm.nih.gov/pubmed/26473852
http://dx.doi.org/10.3390/ijms161024295