Adding Sarcosine to Antipsychotic Treatment in Patients with Stable Schizophrenia Changes the Concentrations of Neuronal and Glial Metabolites in the Left Dorsolateral Prefrontal Cortex

The glutamatergic system is a key point in pathogenesis of schizophrenia. Sarcosine (N-methylglycine) is an exogenous amino acid that acts as a glycine transporter inhibitor. It modulates glutamatergic transmission by increasing glycine concentration around NMDA (N-methyl-d-aspartate) receptors. In...

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Detalles Bibliográficos
Autores principales: Strzelecki, Dominik, Podgórski, Michał, Kałużyńska, Olga, Stefańczyk, Ludomir, Kotlicka-Antczak, Magdalena, Gmitrowicz, Agnieszka, Grzelak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632760/
https://www.ncbi.nlm.nih.gov/pubmed/26501260
http://dx.doi.org/10.3390/ijms161024475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632760/
https://www.ncbi.nlm.nih.gov/pubmed/26501260
http://dx.doi.org/10.3390/ijms161024475

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