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Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol

Analogs of 1,25-dihydroxyergocalciferol, modified in the side-chain and in the A-ring, were tested for their antiproliferative activity against a series of human cancer cell lines in vitro and in vivo toxicity. The proliferation inhibition caused by the analogs was higher than that of the parent com...

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Detalles Bibliográficos
Autores principales: Trynda, Justyna, Turlej, Eliza, Milczarek, Magdalena, Pietraszek, Anita, Chodyński, Michał, Kutner, Andrzej, Wietrzyk, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632780/
https://www.ncbi.nlm.nih.gov/pubmed/26492238
http://dx.doi.org/10.3390/ijms161024873